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Integrating phenotypic and expression profiles to map arsenic-response networks
BACKGROUND: Arsenic is a nonmutagenic carcinogen affecting millions of people. The cellular impact of this metalloid in Saccharomyces cerevisiae was determined by profiling global gene expression and sensitivity phenotypes. These data were then mapped to a metabolic network composed of all known bio...
Autores principales: | Haugen, Astrid C, Kelley, Ryan, Collins, Jennifer B, Tucker, Charles J, Deng, Changchun, Afshari, Cynthia A, Brown, J Martin, Ideker, Trey, Van Houten, Bennett |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545798/ https://www.ncbi.nlm.nih.gov/pubmed/15575969 http://dx.doi.org/10.1186/gb-2004-5-12-r95 |
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