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Targeted α-Particle Radiation Therapy of HER1-Positive Disseminated Intraperitoneal Disease: An Investigation of the Human Anti-EGFR Monoclonal Antibody, Panitumumab

Identifying molecular targets and an appropriate targeting vehicle, i.e., monoclonal antibodies (mAb) and their various forms, for radioimmunotherapy (RIT) remains an active area of research. Panitumumab, a fully human and less immunogenic mAb that binds to the epidermal growth factor receptor (Erb1...

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Detalles Bibliográficos
Autores principales: Milenic, Diane E., Baidoo, Kwamena E., Kim, Young-Seung, Barkley, Rachel, Brechbiel, Martin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458064/
https://www.ncbi.nlm.nih.gov/pubmed/28577439
http://dx.doi.org/10.1016/j.tranon.2017.04.004