An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans

Heat shock protein 90 (Hsp90) is an essential eukaryotic molecular chaperone. To properly chaperone its clientele, Hsp90 proceeds through an ATP-dependent conformational cycle influenced by posttranslational modifications (PTMs) and assisted by a number of co-chaperone proteins. Although Hsp90 confo...

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Detalles Bibliográficos
Autores principales: Zuehlke, Abbey D., Reidy, Michael, Lin, Coney, LaPointe, Paul, Alsomairy, Sarah, Lee, D. Joshua, Rivera-Marquez, Genesis M., Beebe, Kristin, Prince, Thomas, Lee, Sunmin, Trepel, Jane B., Xu, Wanping, Johnson, Jill, Masison, Daniel, Neckers, Len
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458067/
https://www.ncbi.nlm.nih.gov/pubmed/28537252
http://dx.doi.org/10.1038/ncomms15328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458067/
https://www.ncbi.nlm.nih.gov/pubmed/28537252
http://dx.doi.org/10.1038/ncomms15328

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