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CYP2C19 variants and epoxyeicosatrienoic acids in patients with microvascular angina

BACKGROUND: Categorization as a cytochrome P450 (CYP) 2C19 poor metabolizer (PM) is reported to be an independent risk factor for cardiovascular disease. Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid by CYP2C19 epoxygenases and anti-inflammatory properties, especially in micro...

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Detalles Bibliográficos
Autores principales: Akasaka, Tomonori, Sueta, Daisuke, Arima, Yuichiro, Tabata, Noriaki, Takashio, Seiji, Izumiya, Yasuhiro, Yamamoto, Eiichiro, Tsujita, Kenichi, Kojima, Sunao, Kaikita, Koichi, Kajiwara, Ayami, Morita, Kazunori, Oniki, Kentaro, Saruwatari, Junji, Nakagawa, Kazuko, Hokimoto, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458130/
https://www.ncbi.nlm.nih.gov/pubmed/28616567
http://dx.doi.org/10.1016/j.ijcha.2017.03.001