Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9

Toll-like receptors encounter a diversity of degradation products in endosomes. TLR7 and TLR8 have been shown to be activated by RNA degradation products. Here we show that although TLR9 requires single-stranded DNA longer than 20 nucleotides for a robust response, TLR9 activation is augmented by Cp...

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Detalles Bibliográficos
Autores principales: Pohar, Jelka, Lainšček, Duško, Ivičak-Kocjan, Karolina, Cajnko, Miša-Mojca, Jerala, Roman, Benčina, Mojca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458134/
https://www.ncbi.nlm.nih.gov/pubmed/28530246
http://dx.doi.org/10.1038/ncomms15363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458134/
https://www.ncbi.nlm.nih.gov/pubmed/28530246
http://dx.doi.org/10.1038/ncomms15363

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