Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies

CD22-targeted recombinant immunotoxins (rIT) are active in hairy cell leukemia or acute lymphoblastic leukemia (ALL), but not in mantle cell lymphoma (MCL) patients. The goal was to enhance rIT efficacy in vivo and to define a strong combination treatment. Activity of Moxetumomab pasudotox (Moxe) an...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Fabian, Stookey, Stephanie, Cunningham, Tyler, Pastan, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458156/
https://www.ncbi.nlm.nih.gov/pubmed/28423727
http://dx.doi.org/10.18632/oncotarget.16141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458156/
https://www.ncbi.nlm.nih.gov/pubmed/28423727
http://dx.doi.org/10.18632/oncotarget.16141

Ejemplares similares