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Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8(+) T cells by preventing terminal effector differentiation
Long-surviving memory CD8(+) T cells generated by stimulation with appropriate tumor-associated antigens are the most aggressive and persistent tumoricidal effectors. In this event of memory CD8(+) T cell development, the signal transducer and activator of transcription (STAT) proteins function as t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458166/ https://www.ncbi.nlm.nih.gov/pubmed/28430604 http://dx.doi.org/10.18632/oncotarget.15403 |