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Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation

One of the major cellular DNA repair pathways is nucleotide excision repair (NER). It is the primary pathway for repair of various DNA lesions caused by exposure to ultraviolet (UV) light, such as cyclobutane pyrimidine dimers (CPDs) and 6-4 photoproducts. Although lesion-containing DNA associates w...

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Detalles Bibliográficos
Autores principales: Chitale, Shalaka, Richly, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458174/
https://www.ncbi.nlm.nih.gov/pubmed/28416769
http://dx.doi.org/10.18632/oncotarget.16142