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Long-term neurocognitive dysfunction in offspring via NGF/ ERK/CREB signaling pathway caused by ketamine exposure during the second trimester of pregnancy in rats

Early life exposure to ketamine caused neurohistopathologic changes and persistent cognitive dysfunction. For this study, a pregnant rat model was developed to investigate neurocognitive effects in the offspring, following ketamine exposure during the second trimester. Pregnant rats on gestational d...

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Detalles Bibliográficos
Autores principales: Li, Yanan, Li, Xinran, Guo, Cen, Li, Lina, Wang, Yuxin, Zhang, Yiming, Chen, Yu, Liu, Wenhan, Gao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458180/
https://www.ncbi.nlm.nih.gov/pubmed/28415680
http://dx.doi.org/10.18632/oncotarget.16042