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Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head

Alcohol is a leading risk factor for osteonecrosis of the femoral head (ONFH). We explored the molecular mechanisms underlying alcohol-induced ONFH and investigated the protective effect of the novel Akt activator SC-79 against this disease. We found that ethanol inhibited expression of the osteogen...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Xuan, Tao, Shi-Cong, Xu, Zheng-Liang, Yin, Wen-Jing, Zhang, Yue-Lei, Yin, Jun-Hui, Gao, You-Shui, Zhang, Chang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458189/
https://www.ncbi.nlm.nih.gov/pubmed/28415692
http://dx.doi.org/10.18632/oncotarget.16075