The imidazoacridinone C-1311 induces p53-dependent senescence or p53-independent apoptosis and sensitizes cancer cells to radiation

C-1311 is a small molecule, which has shown promise in a number of pre-clinical and clinical studies. However, the biological response to C-1311 exposure is complicated and has been reported to involve a number of cell fates. Here, we investigated the molecular signaling which determines the respons...

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Detalles Bibliográficos
Autores principales: Skwarska, Anna, Ramachandran, Shaliny, Dobrynin, Grzegorz, Leszczynska, Katarzyna B., Hammond, Ester M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458200/
https://www.ncbi.nlm.nih.gov/pubmed/28415717
http://dx.doi.org/10.18632/oncotarget.16102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458200/
https://www.ncbi.nlm.nih.gov/pubmed/28415717
http://dx.doi.org/10.18632/oncotarget.16102

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