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Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion

Activation of Src kinase has been implicated in the pathogenesis of acute brain, liver, and lung injury. However, the role of Src in acute kidney injury (AKI) remains unestablished. To address this, we evaluated the effects of Src inhibition on renal dysfunction and pathological changes in a murine...

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Detalles Bibliográficos
Autores principales: Xiong, Chongxiang, Zang, Xiujuan, Zhou, Xiaoxu, Liu, Lirong, Masucci, Monica V., Tang, Jinhua, Li, Xuezhu, Liu, Na, Bayliss, George, Zhao, Ting C., Zhuang, Shougang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458204/
https://www.ncbi.nlm.nih.gov/pubmed/28415724
http://dx.doi.org/10.18632/oncotarget.16114