PGE(2)/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells

Prostaglandin E(2) (PGE(2)) interacts with tyrosine kinases receptor signaling in both tumor and stromal cells supporting tumor progression. Here we demonstrate that in non-small cell lung carcinoma (NSCLC) cells, A549 and GLC82, PGE(2) promotes nuclear translocation of epidermal growth factor recep...

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Detalles Bibliográficos
Autores principales: Bazzani, Lorenzo, Donnini, Sandra, Finetti, Federica, Christofori, Gerhard, Ziche, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458206/
https://www.ncbi.nlm.nih.gov/pubmed/28415726
http://dx.doi.org/10.18632/oncotarget.16116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458206/
https://www.ncbi.nlm.nih.gov/pubmed/28415726
http://dx.doi.org/10.18632/oncotarget.16116

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