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Mitochondrial VDAC1-based peptides: Attacking oncogenic properties in glioblastoma

Glioblastoma multiforme (GBM), a primary brain malignancy characterized by high morbidity, invasiveness, proliferation, relapse and mortality, is resistant to chemo- and radiotherapies and lacks effective treatment. GBM tumors undergo metabolic reprograming and develop anti-apoptotic defenses. We ta...

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Detalles Bibliográficos
Autores principales: Shteinfer-Kuzmine, Anna, Arif, Tasleem, Krelin, Yakov, Tripathi, Shambhoo Sharan, Paul, Avijit, Shoshan-Barmatz, Varda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458211/
https://www.ncbi.nlm.nih.gov/pubmed/28412744
http://dx.doi.org/10.18632/oncotarget.15455