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Expression of BRCA1 and ERCC1 as predictive clinical outcome after radiochemotherapy in patients with locoregionally moderate-advanced nasopharyngeal carcinoma

In this study, we examined ERCC1 and BRCA1 expression and clinical outcome of 201 phase-III-IV nasopharyngeal carcinoma patients who were treated with cisplatin-based induced chemotherapy and concurrent radiochemotherapy. The chemotherapy response rate of BRCA1(–) and BRCA1(+) patients was 73.6% and...

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Detalles Bibliográficos
Autores principales: Xu, Shan, Yu, Yanxin, Rong, Jinfeng, Hu, Defeng, Zhang, LiJun, Fu, Shaozhi, Yang, Hongru, Fan, Juan, Yang, Linglin, Wu, Jingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458213/
https://www.ncbi.nlm.nih.gov/pubmed/28404895
http://dx.doi.org/10.18632/oncotarget.15565