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Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP27

Cancer stem-like cells (CSCs)/ cancer-initiating cells (CICs) are defined by their higher tumor-initiating ability, self-renewal capacity and differentiation capacity. CSCs/CICs are resistant to several therapies including chemotherapy and radiotherapy. CSCs/CICs thus are thought to be responsible f...

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Detalles Bibliográficos
Autores principales: Yasuda, Kazuyo, Hirohashi, Yoshihiko, Mariya, Tasuku, Murai, Aiko, Tabuchi, Yuta, Kuroda, Takafumi, Kusumoto, Hiroki, Takaya, Akari, Yamamoto, Eri, Kubo, Terufumi, Nakatsugawa, Munehide, Kanaseki, Takayuki, Tsukahara, Tomohide, Tamura, Yasuaki, Hirano, Hiroshi, Hasegawa, Tadashi, Saito, Tsuyoshi, Sato, Noriyuki, Torigoe, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458228/
https://www.ncbi.nlm.nih.gov/pubmed/28415561
http://dx.doi.org/10.18632/oncotarget.16361