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RNAi-mediated inhibition of Lgr5 leads to decreased angiogenesis in gastric cancer

Leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) is a novel gastric cancer marker. However, it is unclear whether it can play roles in tumor angiogenesis. In this study, we aim to investigate the role of Lgr5 on gastric cancer angiogenesis. Lgr5, VEGF expression levels and microves...

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Detalles Bibliográficos
Autores principales: Xi, Hong-Qing, Zhang, Ke-Cheng, Li, Ji-Yang, Cui, Jian-Xin, Gao, Yun-He, Wei, Bo, Huang, Dongsheng, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458231/
https://www.ncbi.nlm.nih.gov/pubmed/28404940
http://dx.doi.org/10.18632/oncotarget.15770