Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation

Deficient production of anti-viral interferons (IFNs) may be involved in causing viral-induced asthma exacerbations. Hence, drugs inducing lung IFN production would be warranted. Azithromycin may reduce asthma exacerbations but its modus operandi is unknown. Here, we investigated if azithromycin ind...

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Detalles Bibliográficos
Autores principales: Menzel, Mandy, Akbarshahi, Hamid, Tufvesson, Ellen, Persson, Carl, Bjermer, Leif, Uller, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458233/
https://www.ncbi.nlm.nih.gov/pubmed/28415826
http://dx.doi.org/10.18632/oncotarget.16364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458233/
https://www.ncbi.nlm.nih.gov/pubmed/28415826
http://dx.doi.org/10.18632/oncotarget.16364

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