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Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats

Hypoxic-ischemic and inflammatory (HII) induces the disruption of blood–brain barrier (BBB) which leads to inflammatory responses and neuronal cell death, resulting in brain secondary damage. Previous studies showed that melatonin produced potent neuroprotective effects in neonatal hypoxic-ischaemic...

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Detalles Bibliográficos
Autores principales: Hu, Yingying, Wang, Zhouguang, Pan, Shulin, Zhang, Hongyu, Fang, Mingchu, Jiang, Huai, Zhang, Hao, Gao, Zhengzheng, Xu, Kebin, Li, Zhenmao, Xiao, Jian, Lin, Zhenlang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458236/
https://www.ncbi.nlm.nih.gov/pubmed/28404943
http://dx.doi.org/10.18632/oncotarget.15780