Cargando…

Niclosamide is a potential therapeutic for familial adenomatosis polyposis by disrupting Axin-GSK3 interaction

The epithelial-mesenchymal transition (EMT) is implicated in tumorigenesis and cancer progression, and canonical Wnt signaling tightly controls Snail, a key transcriptional repressor of EMT. While the suppression of canonical Wnt signaling and EMT comprises an attractive therapeutic strategy, molecu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Sung Yong, Kim, Nam Hee, Lee, Kyungro, Cha, Yong Hoon, Yang, Ji Hye, Cha, So Young, Cho, Eunae Sandra, Lee, Yoonmi, Cha, Jeong Seok, Cho, Hyun Soo, Jeon, Yoon, Yuk, Young-Su, Cho, Suebean, No, Kyoung Tai, Kim, Hyun Sil, Lee, Ho, Choi, Jiwon, Yook, Jong In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458252/
https://www.ncbi.nlm.nih.gov/pubmed/28418862
http://dx.doi.org/10.18632/oncotarget.16252