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Niclosamide is a potential therapeutic for familial adenomatosis polyposis by disrupting Axin-GSK3 interaction
The epithelial-mesenchymal transition (EMT) is implicated in tumorigenesis and cancer progression, and canonical Wnt signaling tightly controls Snail, a key transcriptional repressor of EMT. While the suppression of canonical Wnt signaling and EMT comprises an attractive therapeutic strategy, molecu...
Autores principales: | Ahn, Sung Yong, Kim, Nam Hee, Lee, Kyungro, Cha, Yong Hoon, Yang, Ji Hye, Cha, So Young, Cho, Eunae Sandra, Lee, Yoonmi, Cha, Jeong Seok, Cho, Hyun Soo, Jeon, Yoon, Yuk, Young-Su, Cho, Suebean, No, Kyoung Tai, Kim, Hyun Sil, Lee, Ho, Choi, Jiwon, Yook, Jong In |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458252/ https://www.ncbi.nlm.nih.gov/pubmed/28418862 http://dx.doi.org/10.18632/oncotarget.16252 |
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