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Fhit, a tumor suppressor protein, induces autophagy via 14-3-3τ in non-small cell lung cancer cells

Inactivation of the fragile histidine triad (Fhit) gene has been reported in the majority of human cancers, particularly in lung cancer. The role of Fhit as a tumor suppressor gene has been well documented, and restoration of Fhit expression suppresses tumorigenicity in tumor cell lines and in mouse...

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Detalles Bibliográficos
Autores principales: Lee, Tae-Gul, Jeong, Eun-Hui, Kim, Seo Yun, Kim, Hye-Ryoun, Kim, Hyunggee, Kim, Cheol-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458259/
https://www.ncbi.nlm.nih.gov/pubmed/28404875
http://dx.doi.org/10.18632/oncotarget.16652