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Fhit, a tumor suppressor protein, induces autophagy via 14-3-3τ in non-small cell lung cancer cells
Inactivation of the fragile histidine triad (Fhit) gene has been reported in the majority of human cancers, particularly in lung cancer. The role of Fhit as a tumor suppressor gene has been well documented, and restoration of Fhit expression suppresses tumorigenicity in tumor cell lines and in mouse...
Autores principales: | Lee, Tae-Gul, Jeong, Eun-Hui, Kim, Seo Yun, Kim, Hye-Ryoun, Kim, Hyunggee, Kim, Cheol-Hyeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458259/ https://www.ncbi.nlm.nih.gov/pubmed/28404875 http://dx.doi.org/10.18632/oncotarget.16652 |
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