Identification of small molecule inhibitors of the Aurora-A/TPX2 complex

Aurora kinases are a family of cell division regulators that govern the correct assembly of a bipolar mitotic spindle and the fidelity of chromosome segregation. Their overexpression is associated with genomic instability and aneuploidy, and is frequently observed in cancer. Accordingly, competitive...

Descripción completa

Detalles Bibliográficos
Autores principales: Asteriti, Italia Anna, Daidone, Frederick, Colotti, Gianni, Rinaldo, Serena, Lavia, Patrizia, Guarguaglini, Giulia, Paiardini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458272/
https://www.ncbi.nlm.nih.gov/pubmed/28389630
http://dx.doi.org/10.18632/oncotarget.16738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458272/
https://www.ncbi.nlm.nih.gov/pubmed/28389630
http://dx.doi.org/10.18632/oncotarget.16738

Ejemplares similares