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Identification of small molecule inhibitors of the Aurora-A/TPX2 complex

Aurora kinases are a family of cell division regulators that govern the correct assembly of a bipolar mitotic spindle and the fidelity of chromosome segregation. Their overexpression is associated with genomic instability and aneuploidy, and is frequently observed in cancer. Accordingly, competitive...

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Detalles Bibliográficos
Autores principales:	Asteriti, Italia Anna, Daidone, Frederick, Colotti, Gianni, Rinaldo, Serena, Lavia, Patrizia, Guarguaglini, Giulia, Paiardini, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458272/ https://www.ncbi.nlm.nih.gov/pubmed/28389630 http://dx.doi.org/10.18632/oncotarget.16738

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