Cargando…

Crystal structure of an apremilast ethanol hemisolvate hemihydrate solvatomorph

The title compound, C(22)H(24)N(2)O(7)S·0.5C(2)H(5)OH·0.5H(2)O {systematic name: (S)-4-acetamido-2-[1-(3-eth­oxy-4-meth­oxy­phen­yl)-2-(methyl­sulfon­yl)eth­yl]iso­indo­line-1,3-dione ethanol hemisolvate hemihydrate}, is a novel solvatomorph of apremilast (AP), which is an inhibitor of phosphodieste...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yun-Deng, Liu, Xiao-Hong, Xu, Jian, Zhang, Si-Han, Shen, Kun, Sun, Ling, He, Yong-Mei, Ma, Yan, Zhang, Ai-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458300/
https://www.ncbi.nlm.nih.gov/pubmed/28638635
http://dx.doi.org/10.1107/S2056989017006661