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Crystal structure of an apremilast ethanol hemisolvate hemihydrate solvatomorph
The title compound, C(22)H(24)N(2)O(7)S·0.5C(2)H(5)OH·0.5H(2)O {systematic name: (S)-4-acetamido-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]isoindoline-1,3-dione ethanol hemisolvate hemihydrate}, is a novel solvatomorph of apremilast (AP), which is an inhibitor of phosphodieste...
Autores principales: | Wu, Yun-Deng, Liu, Xiao-Hong, Xu, Jian, Zhang, Si-Han, Shen, Kun, Sun, Ling, He, Yong-Mei, Ma, Yan, Zhang, Ai-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458300/ https://www.ncbi.nlm.nih.gov/pubmed/28638635 http://dx.doi.org/10.1107/S2056989017006661 |
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