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Early Emergence of CD19-Negative Human Antibody-Secreting Cells at the Plasmablast to Plasma Cell Transition

Long-lived human plasma cells (PCs) play central roles in immunity and autoimmunity and are enriched among the subpopulation of CD19(neg) human PCs. However, whether human CD19(neg) PCs are necessarily aged cells that have gradually lost CD19 expression is not known. Assessing peripheral blood sampl...

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Detalles Bibliográficos
Autores principales: Arumugakani, Gururaj, Stephenson, Sophie J., Newton, Darren J., Rawstron, Andy, Emery, Paul, Doody, Gina M., McGonagle, Dennis, Tooze, Reuben M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458329/
https://www.ncbi.nlm.nih.gov/pubmed/28490574
http://dx.doi.org/10.4049/jimmunol.1501761