Selective Pharmacological Augmentation of Hippocampal Activity Produces a Sustained Antidepressant-Like Response without Abuse-Related or Psychotomimetic Effects

BACKGROUND: Selective augmentation of hippocampal activity in ways similar to that caused by ketamine may have therapeutic advantages over ketamine, which has psychotomimetic and reinforcing effects likely due to effects outside the hippocampus (i.e., off-target effects). METHODS: Here we evaluated...

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Detalles Bibliográficos
Autores principales: Carreno, Flavia R., Collins, Gregory T., Frazer, Alan, Lodge, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458335/
https://www.ncbi.nlm.nih.gov/pubmed/28339593
http://dx.doi.org/10.1093/ijnp/pyx003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458335/
https://www.ncbi.nlm.nih.gov/pubmed/28339593
http://dx.doi.org/10.1093/ijnp/pyx003

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