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MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes

OBJECTIVE: Decreased expression of collagen type II in favour of collagen type I or X is one hallmark of chondrocyte phenotype changes in osteoarthritic (OA) cartilage. MicroRNA- (miR-) 29b was previously shown to target collagens in several tissues. We studied whether it could contribute to collage...

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Detalles Bibliográficos
Autores principales: Moulin, David, Salone, Véronique, Koufany, Meriem, Clément, Thomas, Behm-Ansmant, Isabelle, Branlant, Christiane, Charpentier, Bruno, Jouzeau, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458373/
https://www.ncbi.nlm.nih.gov/pubmed/28612031
http://dx.doi.org/10.1155/2017/9792512