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A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action

PCPS from P. citrinopileatus mushroom extract is a β-1,6-glucan possessing a proinflammatory effect on innate immune cells. The PCPS stimulated THP-1 macrophages to secrete significant levels of TNF. Moreover, the mRNA expressions of TNF and IL-1β were significantly enhanced by PCPS treatment. Howev...

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Detalles Bibliográficos
Autores principales: Minato, Ken-ichiro, Ohara, Akihiro, Mizuno, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458384/
https://www.ncbi.nlm.nih.gov/pubmed/28611507
http://dx.doi.org/10.1155/2017/8402405