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Crystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA

Neisserial heparin-binding antigen (NHBA) is a surface-exposed lipoprotein from Neisseria meningitidis and is a component of the meningococcus B vaccine Bexsero. As part of a study to characterize the three-dimensional structure of NHBA and the molecular basis of the human immune response to Bexsero...

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Detalles Bibliográficos
Autores principales: Maritan, Martina, Cozzi, Roberta, Lo Surdo, Paola, Veggi, Daniele, Bottomley, Matthew James, Malito, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458386/
https://www.ncbi.nlm.nih.gov/pubmed/28580917
http://dx.doi.org/10.1107/S2053230X17006021