Glycosyl chains and 25‐hydroxycholesterol contribute to the intracellular transport of amyloid beta (Aβ‐42) in Jurkat T cells

Amyloid beta (Aβ) is a peptide responsible for the development of Alzheimer's disease (AD). Misfolding and accumulation of endogenous Aβ can lead to neural cell apoptosis through endoplasmic reticulum (ER) stress. Added exogenous Aβ can also result in ER stress, leading to neurotoxicity and apo...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Neha, Baek, KeangOK, Phan, Huong T.T., Shimokawa, Naofumi, Takagi, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458452/
https://www.ncbi.nlm.nih.gov/pubmed/28593141
http://dx.doi.org/10.1002/2211-5463.12234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458452/
https://www.ncbi.nlm.nih.gov/pubmed/28593141
http://dx.doi.org/10.1002/2211-5463.12234

Ejemplares similares