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Glycosyl chains and 25‐hydroxycholesterol contribute to the intracellular transport of amyloid beta (Aβ‐42) in Jurkat T cells
Amyloid beta (Aβ) is a peptide responsible for the development of Alzheimer's disease (AD). Misfolding and accumulation of endogenous Aβ can lead to neural cell apoptosis through endoplasmic reticulum (ER) stress. Added exogenous Aβ can also result in ER stress, leading to neurotoxicity and apo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458452/ https://www.ncbi.nlm.nih.gov/pubmed/28593141 http://dx.doi.org/10.1002/2211-5463.12234 |