DNA‐induced unfolding of the thyroid hormone receptor α A/B domain through allostery

The A/B domains of nuclear receptors such as thyroid receptor α (TRα) are considered to be conformationally flexible and can potentially adopt multiple structural conformations. We used intrinsic tryptophan fluorescence quenching and circular dichroism spectroscopy to characterize the unfolding of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandez, Elias J., Gahlot, Vandna, Rodriguez, Celeste, Amburn, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458466/
https://www.ncbi.nlm.nih.gov/pubmed/28593140
http://dx.doi.org/10.1002/2211-5463.12229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458466/
https://www.ncbi.nlm.nih.gov/pubmed/28593140
http://dx.doi.org/10.1002/2211-5463.12229

Ejemplares similares