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Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

BACKGROUND: Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary melanoma is performed using histological biomarkers such as tumor thickness and ulceration. As disruption of the epigenomic landscape is recognize...

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Detalles Bibliográficos
Autores principales: Wouters, Jasper, Vizoso, Miguel, Martinez-Cardus, Anna, Carmona, F. Javier, Govaere, Olivier, Laguna, Teresa, Joseph, Jesuchristopher, Dynoodt, Peter, Aura, Claudia, Foth, Mona, Cloots, Roy, van den Hurk, Karin, Balint, Balazs, Murphy, Ian G., McDermott, Enda W., Sheahan, Kieran, Jirström, Karin, Nodin, Bjorn, Mallya-Udupi, Girish, van den Oord, Joost J., Gallagher, William M., Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458482/
https://www.ncbi.nlm.nih.gov/pubmed/28578692
http://dx.doi.org/10.1186/s12916-017-0851-3