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The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design
Recent developments in electron microscopy (EM) have led to a step change in our ability to solve the structures of previously intractable systems, especially membrane proteins and large protein complexes. This has provided new opportunities in the field of structure-based drug design, with a number...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458495/ https://www.ncbi.nlm.nih.gov/pubmed/28580915 http://dx.doi.org/10.1107/S2059798317004077 |