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A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions

Several large-scale efforts have systematically catalogued protein-protein interactions (PPIs) of a cell in a single environment. However, little is known about how the protein interactome changes across environmental perturbations. Current technologies, which assay one PPI at a time, are too low th...

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Detalles Bibliográficos
Autores principales: Schlecht, Ulrich, Liu, Zhimin, Blundell, Jamie R., St.Onge, Robert P., Levy, Sasha F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458509/
https://www.ncbi.nlm.nih.gov/pubmed/28541284
http://dx.doi.org/10.1038/ncomms15586