Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi

RNAi is a conserved mechanism in which small RNAs induce silencing of complementary targets. How Argonaute-bound small RNAs are targeted for degradation is not well understood. We show that the adenyl-transferase Cid14, a member of the TRAMP complex, and the uridyl-transferase Cid16 add non-template...

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Detalles Bibliográficos
Autores principales: Pisacane, Paola, Halic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458512/
https://www.ncbi.nlm.nih.gov/pubmed/28541282
http://dx.doi.org/10.1038/ncomms15332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458512/
https://www.ncbi.nlm.nih.gov/pubmed/28541282
http://dx.doi.org/10.1038/ncomms15332

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