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Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
RNAi is a conserved mechanism in which small RNAs induce silencing of complementary targets. How Argonaute-bound small RNAs are targeted for degradation is not well understood. We show that the adenyl-transferase Cid14, a member of the TRAMP complex, and the uridyl-transferase Cid16 add non-template...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458512/ https://www.ncbi.nlm.nih.gov/pubmed/28541282 http://dx.doi.org/10.1038/ncomms15332 |