Digital logic circuits in yeast with CRISPR-dCas9 NOR gates

Natural genetic circuits enable cells to make sophisticated digital decisions. Building equally complex synthetic circuits in eukaryotes remains difficult, however, because commonly used components leak transcriptionally, do not arbitrarily interconnect or do not have digital responses. Here, we des...

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Detalles Bibliográficos
Autores principales: Gander, Miles W., Vrana, Justin D., Voje, William E., Carothers, James M., Klavins, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458518/
https://www.ncbi.nlm.nih.gov/pubmed/28541304
http://dx.doi.org/10.1038/ncomms15459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458518/
https://www.ncbi.nlm.nih.gov/pubmed/28541304
http://dx.doi.org/10.1038/ncomms15459

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