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Cytotoxic effects of docetaxel as a candidate drug of drug-eluting stent on human umbilical vein endothelial cells and the signaling pathway of cell migration inhibition, adhesion delay and shape change

Docetaxel (DTX), a paclitaxel analogue, can efficiently inhibit proliferation of vascular smooth muscle cells and has broadly been used as an antiangiogenesis drug. However, as a candidate drug of drug-eluting stent, the effects of DTX on human umbilical vein endothelial cells (HUVECs) are still not...

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Detalles Bibliográficos
Autores principales: Hu, Tingzhang, Yang, Chun, Fu, Meiling, Yang, Jiali, Du, Rolin, Ran, Xiaolin, Yin, Tieying, Wang, Guixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458539/
https://www.ncbi.nlm.nih.gov/pubmed/28596914
http://dx.doi.org/10.1093/rb/rbx010