Design of live attenuated bacterial vaccines based on D-glutamate auxotrophy

Vaccine development is a priority for global health due to the growing multidrug resistance in bacteria. D-glutamate synthesis is essential for bacterial cell wall formation. Here we present a strategy for generating effective bacterial whole-cell vaccines auxotrophic for D-glutamate. We apply this...

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Detalles Bibliográficos
Autores principales: Cabral, Maria P., García, Patricia, Beceiro, Alejandro, Rumbo, Carlos, Pérez, Astrid, Moscoso, Miriam, Bou, Germán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458566/
https://www.ncbi.nlm.nih.gov/pubmed/28548079
http://dx.doi.org/10.1038/ncomms15480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458566/
https://www.ncbi.nlm.nih.gov/pubmed/28548079
http://dx.doi.org/10.1038/ncomms15480

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