MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47(phox)–oxidative stress pathway in neutrophils

OBJECTIVES: Chronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of the most abundant microRNAs (miRNAs) in neutrophils,...

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Detalles Bibliográficos
Autores principales: Li, Man, He, Yong, Zhou, Zhou, Ramirez, Teresa, Gao, Yueqiu, Gao, Yanhang, Ross, Ruth A, Cao, Haixia, Cai, Yan, Xu, Mingjiang, Feng, Dechun, Zhang, Ping, Liangpunsakul, Suthat, Gao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458746/
https://www.ncbi.nlm.nih.gov/pubmed/27679493
http://dx.doi.org/10.1136/gutjnl-2016-311861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458746/
https://www.ncbi.nlm.nih.gov/pubmed/27679493
http://dx.doi.org/10.1136/gutjnl-2016-311861

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