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MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47(phox)–oxidative stress pathway in neutrophils
OBJECTIVES: Chronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of the most abundant microRNAs (miRNAs) in neutrophils,...
Autores principales: | Li, Man, He, Yong, Zhou, Zhou, Ramirez, Teresa, Gao, Yueqiu, Gao, Yanhang, Ross, Ruth A, Cao, Haixia, Cai, Yan, Xu, Mingjiang, Feng, Dechun, Zhang, Ping, Liangpunsakul, Suthat, Gao, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458746/ https://www.ncbi.nlm.nih.gov/pubmed/27679493 http://dx.doi.org/10.1136/gutjnl-2016-311861 |
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