Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia

The autologous ALDH bright (ALDH(br)) cell therapy for ischemic injury is clinically safe and effective, while the underlying mechanism remains elusive. Here, we demonstrated that the glycolysis dominant metabolism of ALDH(br) cells is permissive to restore blood flow in an ischemic hind limb model...

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Detalles Bibliográficos
Autores principales: Sun, Xiaolei, Zhu, Hong, Dong, Zhen, Liu, Xiangwei, Ma, Xin, Han, Shasha, Lu, Fei, Wang, Peng, Qian, Sanli, Wang, Cong, Shen, Cheng, Zhao, Xiaona, Zou, Yunzeng, Ge, Junbo, Sun, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458766/
https://www.ncbi.nlm.nih.gov/pubmed/28582728
http://dx.doi.org/10.1016/j.redox.2017.05.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458766/
https://www.ncbi.nlm.nih.gov/pubmed/28582728
http://dx.doi.org/10.1016/j.redox.2017.05.018

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