Cargando…

Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia

The autologous ALDH bright (ALDH(br)) cell therapy for ischemic injury is clinically safe and effective, while the underlying mechanism remains elusive. Here, we demonstrated that the glycolysis dominant metabolism of ALDH(br) cells is permissive to restore blood flow in an ischemic hind limb model...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Xiaolei, Zhu, Hong, Dong, Zhen, Liu, Xiangwei, Ma, Xin, Han, Shasha, Lu, Fei, Wang, Peng, Qian, Sanli, Wang, Cong, Shen, Cheng, Zhao, Xiaona, Zou, Yunzeng, Ge, Junbo, Sun, Aijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458766/ https://www.ncbi.nlm.nih.gov/pubmed/28582728 http://dx.doi.org/10.1016/j.redox.2017.05.018

Ejemplares similares

Aberrant Hypermethylation of Aldehyde Dehydrogenase 2 Promoter Upstream Sequence in Rats with Experimental Myocardial Infarction
por: Wang, Peng, et al.
Publicado: (2015)

Aldehyde Dehydrogenase 2 (ALDH2) Elicits Protection against Pulmonary Hypertension via Inhibition of ERK1/2-Mediated Autophagy
por: Chang, Suchi, et al.
Publicado: (2022)

Update on the aldehyde dehydrogenase gene (ALDH) superfamily
por: Jackson, Brian, et al.
Publicado: (2011)

Aldehyde Dehydrogenase 2 (ALDH2) in Rat Fatty Liver Cold Ischemia Injury
por: Panisello-Roselló, Arnau, et al.
Publicado: (2018)

The roles of aldehyde dehydrogenases (ALDHs) in the PDH bypass of Arabidopsis
por: Wei, Yanling, et al.
Publicado: (2009)

Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family
por: Vasiliou, Vasilis, et al.
Publicado: (2005)

Genome-Wide Identification and Analysis of Grape Aldehyde Dehydrogenase (ALDH) Gene Superfamily
por: Zhang, Yucheng, et al.
Publicado: (2012)

The Activity of Alcohol Dehydrogenase (ADH) Isoenzymes and Aldehyde Dehydrogenase (ALDH) in the Sera of Patients with Brain Cancer
por: Jelski, Wojciech, et al.
Publicado: (2014)

Salivary Aldehyde Dehydrogenase: Activity towards Aromatic Aldehydes and Comparison with Recombinant ALDH3A1
por: Giebułtowicz, Joanna, et al.
Publicado: (2009)

Low Km aldehyde dehydrogenase (ALDH2) polymorphism, alcohol-drinking behavior, and chromosome alterations in peripheral lymphocytes.
por: Morimoto, K, et al.
Publicado: (1996)

Accumulation of endogenous adenosine improves cardiomyocyte metabolism via epigenetic reprogramming in an ischemia-reperfusion model
por: Wang, Peng, et al.
Publicado: (2023)

Mining distinct aldehyde dehydrogenase 1 (ALDH1) isoenzymes in gastric cancer
por: Shen, Jia-Xin, et al.
Publicado: (2016)

Comprehensive Analysis of Aldehyde Dehydrogenases (ALDHs) and Its Significant Role in Hepatocellular Carcinoma
por: Yao, Senbang, et al.
Publicado: (2021)

Aldehydes, Aldehyde Metabolism, and the ALDH2 Consortium
por: Rwere, Freeborn, et al.
Publicado: (2022)

Aldehyde dehydrogenase 1 (ALDH1) isoform expression and potential clinical implications in hepatocellular carcinoma
por: Yang, Cheng–kun, et al.
Publicado: (2017)

Aldehyde dehydrogenase 2 activation ameliorates CCl(4)‐induced chronic liver fibrosis in mice by up‐regulating Nrf2/HO‐1 antioxidant pathway
por: Ma, Xin, et al.
Publicado: (2018)

Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung
por: Kuroda, Aoi, et al.
Publicado: (2017)

Overexpression of the Aldehyde Dehydrogenase Gene ZmALDH Confers Aluminum Tolerance in Arabidopsis thaliana
por: Du, Han-Mei, et al.
Publicado: (2022)

The diagnostic value of alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) measurement in the sera of patients with brain tumor
por: Jelski, Wojciech, et al.
Publicado: (2017)

Impact and potential mechanism of effects of chronic moderate alcohol consumption on cardiac function in aldehyde dehydrogenase 2 gene heterozygous mice
por: Hu, Qinfeng, et al.
Publicado: (2022)

Identification of cancer-type specific expression patterns for active aldehyde dehydrogenase (ALDH) isoforms in ALDEFLUOR assay
por: Zhou, Lei, et al.
Publicado: (2018)

The Activity of Class I, II, III and IV of Alcohol Dehydrogenase (ADH) Isoenzymes and Aldehyde Dehydrogenase (ALDH) in Brain Cancer
por: Laniewska-Dunaj, Magdalena, et al.
Publicado: (2013)

The combination of aldehyde dehydrogenase 1 (ALDH1) and CD44 is associated with poor outcomes in endometrial cancer
por: Huang, Hsin-Hui, et al.
Publicado: (2018)

Aldehyde Dehydrogenase (ALDH) Activity Does Not Select for Cells with Enhanced Aggressive Properties in Malignant Melanoma
por: Prasmickaite, Lina, et al.
Publicado: (2010)

Determination of Aldehyde Dehydrogenase (ALDH) Isozymes in Human Cancer Samples - Comparison of Kinetic and Immunochemical Assays
por: Wroczynski, Piotr, et al.
Publicado: (2002)

The mitochondrial aldehyde dehydrogenase OsALDH2b negatively regulates tapetum degeneration in rice
por: Xie, Xianrong, et al.
Publicado: (2020)

Origin and Spread of the ALDH2 Glu504Lys Allele
por: Zhang, Xiaokai, et al.
Publicado: (2021)

Associations between aldehyde dehydrogenase 2 (ALDH2) rs671 genetic polymorphisms, lifestyles and hypertension risk in Chinese Han people
por: Ma, Cong, et al.
Publicado: (2017)

Aldehyde dehydrogenase 1 (ALDH1) immunostaining in axillary lymph node metastases is an independent prognostic factor in ALDH1-positive breast cancer
por: Guan, Xin, et al.
Publicado: (2021)

Interferon-gamma inhibits aldehyde dehydrogenase(bright) cancer stem cells in the 4T1 mouse model of breast cancer
por: Zhuang, Xiufen, et al.
Publicado: (2022)

Aldehyde dehydrogenase 1 (ALDH1) expression is an independent prognostic factor in triple negative breast cancer (TNBC)
por: Ma, Fei, et al.
Publicado: (2017)

Characteristics and Expression Patterns of the Aldehyde Dehydrogenase (ALDH) Gene Superfamily of Foxtail Millet (Setaria italica L.)
por: Zhu, Chen, et al.
Publicado: (2014)

Aldehyde Dehydrogenase 1 (ALDH1) Is a Potential Marker for Cancer Stem Cells in Embryonal Rhabdomyosarcoma
por: Nakahata, Kengo, et al.
Publicado: (2015)

Genome-Wide Identification and Functional Classification of Tomato (Solanum lycopersicum) Aldehyde Dehydrogenase (ALDH) Gene Superfamily
por: Jimenez-Lopez, Jose C., et al.
Publicado: (2016)

Aldehyde Dehydrogenase 2 (ALDH2) Genotype Affects Rectal Cancer Susceptibility Due to Alcohol Consumption
por: Matsuo, Keitaro, et al.
Publicado: (2007)

Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway
por: Zhao, Xiaona, et al.
Publicado: (2016)

Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations
por: Peng, Giia-Sheun, et al.
Publicado: (2009)

Acetylation of aldehyde dehydrogenase ALDH1L2 regulates cellular redox balance and the chemosensitivity of colorectal cancer to 5-fluorouracil
por: Li, Chaoqun, et al.
Publicado: (2023)

Ovarian Cancer Stem Cells Are Enriched in Side Population and Aldehyde Dehydrogenase Bright Overlapping Population
por: Yasuda, Kazuyo, et al.
Publicado: (2013)

Differential expression of aldehyde dehydrogenase 1a1 (ALDH1) in normal ovary and serous ovarian tumors
por: Penumatsa, Krishna, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ld3ek5qtkn9qcm46263rsau4u9