Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex

ASPM/Asp/ASPM-1 is a microcephaly-associated protein family that regulates spindle architecture, but the underlying mechanism is poorly understood. Here, we show that ASPM forms a complex with another protein linked to microcephaly, the microtubule severing ATPase katanin. ASPM and katanin localize...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Kai, Rezabkova, Lenka, Hua, Shasha, Liu, Qingyang, Capitani, Guido, Altelaar, A. F. Maarten, Heck, Albert J. R., Kammerer, Richard A., Steinmetz, Michel O., Akhmanova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458804/
https://www.ncbi.nlm.nih.gov/pubmed/28436967
http://dx.doi.org/10.1038/ncb3511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458804/
https://www.ncbi.nlm.nih.gov/pubmed/28436967
http://dx.doi.org/10.1038/ncb3511

Ejemplares similares