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Action of YM155 on clear cell renal cell carcinoma does not depend on survivin expression levels

The dioxonapthoimidazolium YM155 is a survivin suppressant which has been investigated as an anticancer agent in clinical trials. Here, we investigated its growth inhibitory properties on a panel of immortalized and patient derived renal cell carcinoma (RCC) cell lines which were either deficient in...

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Detalles Bibliográficos
Autores principales: Sim, Mei Yi, Huynh, Hung, Go, Mei Lin, Yuen, John Shyi Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459331/
https://www.ncbi.nlm.nih.gov/pubmed/28582447
http://dx.doi.org/10.1371/journal.pone.0178168