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Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation
Expression of C1q, an early component of the classical complement pathway, has been shown to be induced in neurons in hippocampal slices, following accumulation of exogenous Aβ42. Microglial activation was also detected by surface marker expression and cytokine production. To determine whether C1q i...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545941/ https://www.ncbi.nlm.nih.gov/pubmed/15642121 http://dx.doi.org/10.1186/1742-2094-2-1 |